GodAandScience.orgScientific Evidence for Answered Prayer and the Existence of God
by Rich Deem

A Report on the Papers:

  1. "Positive Therapeutic Effects of Intercessory Prayer in a Coronary Care Unit Population"1
  2. "A Randomized, Controlled Trial of the Effects of Remote, Intercessory Prayer on Outcomes in Patients Admitted to the Coronary Care Unit"2
  3. Does Prayer Influence the Success of in Vitro Fertilization–Embryo Transfer? Report of a Masked, Randomized Trial (new)3 

What scientific evidence do we have that God exists? A crucial doctrine of Christianity is that God listens to and answers prayers. So why not test this doctrine scientifically, using a double-blind, clinical trial? This is the exact premise that two groups of cardiac doctors used in double-blind "drug" studies of the efficacy of Christian prayer on healing. Both papers are available online.

1. "Positive Therapeutic Effects of Intercessory Prayer in a Coronary Care Unit Population"

Methods

Cardiac patients from the San Francisco General Medical Center were randomly divided (using a computer-generated list) into two groups. The names of the patients in the "test" group were given to a group of Christians, who prayed for them while they were in the hospital. The intercessory prayer team members were chosen on the following basis:

  1. Born again Christians on the basis of John 3:34
  2. Led an active Christian life on the basis of
    1. daily devotional prayer
    2. fellowship in a local Christian church

The "placebo" group received no prayer. Neither the "test" nor the "placebo" group of patients knew if they were receiving prayer. Likewise, the hospital staff, doctors, or nurses were "blinded" since they did not know which patient belonged to which group.

Results

Statistics were acquired from the prayer and placebo groups both before and after prayer, until the patients were discharged from the hospital. There were no statistical differences between the placebo and the prayer groups before prayer was initiated. The results demonstrated that patients who were prayed for suffered "less congestive heart failure, required less diuretic and antibiotic therapy, had fewer episodes of pneumonia, had fewer cardiac arrests, and were less frequently intubated and ventilated." Statistics demonstrated the the prayer group had a statistically significantly lower severity score based upon the hospital course after entry (p < 0.01). Multivariate analysis of all the parameters measured demonstrated that the outcomes of the two groups were even more statistically significant (p < 0.0001). In science, the standard level of significance is when a "p value" is less than 0.05. A value of 0.01 means that the likelihood the result is because of chance is one in 100. A p value of 0.0001 indicates that in only one study out of 10,000 is the result likely to be due to chance. Table 2 from the study is reproduced below. The remarkable thing which one notices is that nearly every parameter measured is affected by prayer, although individually many categories do not reach the level of statistical significance due to sample size. However, multivariate analysis, which compares all parameters together produces a level of significance seldom reached in any scientific study (p < 0.0001). The author points out that the method used in this study does not produce the maximum effect of prayer, since the study could not control for the effect of outside prayer (i.e., it is likely many of the placebo group were prayed for by persons outside of the study). It is likely that a study which used only atheists (who had no Christian family or friends) would produce an even more dramatic result. However, since atheists make up only 1-2% of the population, it would be difficult to obtain a large enough sample size.


TABLE 2. Results of Intercessory Prayer


Study Variable

Intercessory
Prayer

Control
Group


P


Days in CCU after entry

2.0 ± 2.5

2.4 ± 4.1

NS

Days in hospital after entry

7.6 ± 8.9

7.6 ± 8.7

NS

Number of discharge medications

3.7 ± 2.2

4.0 ± 2.4

NS


New Problems, Diagnoses, and
Therapeutic Events After Entry


% (No.)


% (No.)


P


Antiarrhythmics

9(17)

13 (27)

NS

Coronary angiography

9 (17)

11 (21)

NS

VT/VF

7 (14)

9 (17)

NS

Readmissions to CCU

7 (14)

7 (14)

NS

Mortality

7 (13)

9 (17)

NS

Congestive heart failure

4 (8)

10 (20)

<0.01

Inotropic agents

4 (8)

8 (16)

NS

Vasodilators

4 (8)

6 (12)

NS

Supraventricular tachyarrhythmia

4 (8)

8 (15)

NS

Arterial pressure monitoring

4 (7)

8 (15)

NS

Central pressure monitoring

3 (6)

7 (15)

NS

Diuretics

3 (5)

8 (15)

<0.01

Major surgery before discharge

3 (5)

7 (14)

NS

Temporary pacemaker

2 (4)

1 (1)

NS

Sepsis

2 (4)

4 (7)

NS

Cardiopulmonary arrest

2 (3)

7 (14)

<0.01

Third-degree heart block

2 (3)

1 (2)

NS

Pneumonia

2 (3)

7 (13)

<0.01

Hypotension (systolic <90 torr)

2 (3)

4 (7)

NS

Extension of infarction

2 (3)

3 (6)

NS

Antibiotics

2 (3)

9 (17)

<0.01

Permanent pacemaker

2 (3)

1 (1)

NS

Gastrointestinal bleeding

1 (1)

2 (3)

NS

Intubation/ventilation

0 (0)

6 (12)

<0.01


NS = P > .05; VT/VF = ventricular tachycardia or ventricular fibrillation

2. "A Randomized, Controlled Trial of the Effects of Remote, Intercessory Prayer on Outcomes in Patients Admitted to the Coronary Care Unit"

Methods

Cardiac patients from the CCU at the Mid America Heart Institute (MAHI), Kansas City, Mo, were randomly chosen and assigned to control or prayer groups. In this study, patients were not told about the prayer study and doctors did not know which patients were assigned to which groups. According to the paper, "The intercessors represented a variety of Christian traditions, with 35% listing their affiliations as nondenominational, 27% as Episcopalian, and the remainder as other Protestant groups or Roman Catholic. Unlike the Byrd study, the intercessors of the MAHI study were given no details about the medical conditions of the patients, but were only given their first name.

Results

The main table of results, reproduced from the study appears as Table 3 below. Because of the small sample size of each individual component, only one of the individual components reached statistical significance. However, the overall effect was statistically significant, with a P value of 0.04, meaning that the result was likely to occur by chance in only 1 out of 25 times the experiment was repeated. 

Table 3. Effects of Intercessory Prayer on Individual Components of the Mid America Heart Institute–Cardiac Care Unit (MAHI-CCU) Score*

No. (%) of Patients

MAHI-CCU Score Component Usual Care Group
(n = 524)
Prayer Group
(n = 466)
P

Antianginal agents 59 (11.3) 47 (10.1) .62
Antibiotics 82 (15.6) 77 (16.5) .77
Unstable angina 4 (0.8) 1 (0.2) .38
Arterial monitor 42 (8.0) 32 (6.9) .57
Catheterization 180 (34.4) 162 (34.8) .94
Antiarrhythmics 56 (10.7) 50 (10.7) .94
Inotropes 76 (14.5) 69 (14.8) .96
Vasodilation 78 (14.9) 59 (12.7) .36
Diuretics 112 (21.4) 97 (20.8) .89
Pneumonia 10 (1.9) 12 (2.6) .62
Atrial fibrillation 17 (3.2) 12 (2.6) .66
Supraventricular tachycardia 6 (1.1) 2 (0.4) .29
Hypotension 7 (1.3) 8 (1.7) .82
Anemia/transfusion 66 (12.6) 50 (10.7) .42
Temporary pacer 16 (3.0) 13 (2.8) .95
Third-degree heart block 1 (0.2) 2 (0.4) .60
Readmit to cardiac care unit 22 (4.2) 25 (5.4) .48
Swan-Ganz catheter 172 (32.8) 123 (26.4) .03
Implanted cardiac defibrillator 6 (1.1) 10 (2.1) .32
Electrophysiology study 15 (2.9) 10 (2.1) .61
Radiofrequency ablation 8 (1.5) 2 (0.4) .11
Extension of infarct 2 (0.4) 0 (0.0) .50
Gastrointestinal bleed 12 (2.3) 5 (1.1) .22
Interventional coronary procedure 155 (29.6) 121 (26.0) .21
PTCA alone 69 (13.2) 62 (13.3) .95
PTCA with stent and/or rotablator 86 (16.4) 59 (12.7) .10
Permanent pacer 21 (4.0) 12 (2.6) .28
Congestive heart failure 17 (3.2) 19 (4.1) .60
Ventricular fibrillation/tachycardia 12 (2.3) 10 (2.1) .95
Intra-aortic balloon pump 20 (3.8) 12 (2.6) .36
Major surgery 76 (14.5) 51 (10.9) .11
Sepsis 7 (1.3) 7 (1.5) .96
Intubation/ventilation 27 (5.2) 26 (5.6) .88
Cardiac arrest 6 (1.1) 5 (1.1) .84
Death 46 (8.8) 42 (9.0) .99
* PTCA indicates percutaneous transluminal coronary angioplasty.


3. "Does Prayer Influence the Success of in Vitro Fertilization–Embryo Transfer? Report of a Masked, Randomized Trial"

Methods

This study was designed as a prospective, randomized, double-blind study in which the efficacy of intercessory prayer was assessed in patients undergoing treatment for in vitro fertilization–embryo transfer (IVF-ET), who were unaware of the study (Patients are required to be informed of being involved in a research study conducted in the USA, but since this study was performed in South Korea, informed consent was not obtained). Investigators chose the setting of IVF-ET in order to control for as many variables as possible and designed the study to be masked to patients, providers and investigators. According to the authors of the study:

"In planning and conducting this trial in as rigorous a fashion as possible, we set out with the expectation that we would show no benefit of IP. None of the authors are employed by religious organizations, and we were not asked by any religious groups to conduct this trial, nor did we seek religious advice at any time."

Two hundred nineteen women, aged 26–46 were prospectively but blindly enrolled into the randomized trial to test the effect of intercessory prayer on IVF-ET. These women were consecutively treated between December 1998 and March 1999 at the Cha General Hospital, Seoul, Korea. As in the previous two studies, all prayer participants in this study were from Christian denominations.

Results:

Table 1 shows that the two groups (NIP, no intercessory prayer, and IP, intercessory prayer) were statistically indistinguishable as randomized into their respective groups. The NIP group obtained a pregnancy rate of 26%, which is average for IVF-ET. However, the prayer group had nearly a doubling in their success rate (50%). These results were extremely significant (p = 0.0013). In addition, the implantation rate was significantly higher in the IP group (16.3% vs. 8%, P = 0.0005), and a greater number of preembryos reached the eight-cell stage in the IP group (66% vs. 45.5%, P = 0.0001).

Table 1  Profile of Patients
Profile NIP IP
No. of patients (ET cycle) 81 (81) 88 (88)
No. of patients (ET cycle) 81 (81) 88 (88)
Mean (± SD) age (yr) 34.8 ± 4.4 33.9 ± 4.7
Duration of infertility (yr) 5.3 ± 4.0 4.6 ± 2.8
No. of oocytes retrieved 10.0 ± 5.9 11.4 ± 7.2
No. of oocytes fertilized 7.7 ± 4.9 8.9 ± 6.2
No. of oocytes transferred 4.3 ±1.4 4.3 ±1.2
No. of pregnancies/ETcycle (%) 21/18 (26) 44/88 (50)*

Values are mean ± SD
*P = 0.0013

 

Implications of the studies

Obviously, science has demonstrated in three separate studies the efficacy of Christian prayer in medical studies. There is no "scientific" (non-spiritual) explanation for the cause of the medical effects demonstrated in these studies. The only logical, but not testable, explanation is that God exists and answers the prayers of Christians. No other religion has succeeded in scientifically demonstrating that prayer to their God has any efficacy in healing. The Bible declares that Jesus Christ has power over life and death and sickness and is able to heal us, both physically5 and spiritually.6 He gave this power to His disciples and those who follow Him.7

Related Page

Scientific Studies that Show a Positive Effect of Religion on Health - Not Convinced? There's much more!

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References:

  1. Byrd, R.C. 1988. Positive Therapeutic Effects of Intercessory Prayer in a Coronary Care Unit Population. Southern Medical Journal 81: 826-829. [online paper]
  2. Harris, W.S., Gowda, M., Kolb, J.W., Strychacz, C.P., Vacek, J.L., Jones, P.G., Forker, A., O’Keefe, J.H., and McCallister, B.D. 1999. A Randomized, Controlled Trial of the Effects of Remote, Intercessory Prayer on Outcomes in Patients Admitted to the Coronary Care Unit. Arch Intern Med. 159:2273-2278. [PDF version]
  3. Cha, K.Y., D. P. Wirth, and R. A. Lobo. 2001. Does Prayer Influence the Success of in Vitro Fertilization–Embryo Transfer? Report of a Masked, Randomized Trial. Journal of Reproductive Medicine 49:.(http://www.reproductivemedicine.com/Features/Feature.htm)
  4. Jesus answered and said to him, "Truly, truly, I say to you, unless one is born again, he cannot see the kingdom of God." (John 3:3)
  5. And Jesus was going about in all Galilee, teaching in their synagogues, and proclaiming the gospel of the kingdom, and healing every kind of disease and every kind of sickness among the people. (Matthew 4:23)
    And Jesus was going about all the cities and the villages, teaching in their synagogues, and proclaiming the gospel of the kingdom, and healing every kind of disease and every kind of sickness. (Matthew 9:35)
  6. "But in order that you may know that the Son of Man has authority on earth to forgive sins," He said to the paralytic. (Mark 2:10)
    and He said to them, "Thus it is written, that the Christ should suffer and rise again from the dead the third day; and that repentance for forgiveness of sins should be proclaimed in His name to all the nations, beginning from Jerusalem. (Luke 24:46-47)
  7. And He called the twelve together, and gave them power and authority over all the demons, and to heal diseases. And He sent them out to proclaim the kingdom of God, and to perform healing. (Luke 9:1-2)

Related Links:

  1. Harold G. Koenig, M.D., M.H.Sc., Linda K. George, Ph.D., and Bercedis L. Peterson, Ph.D. 1998. Religiosity and Remission of Depression in Medically Ill Older Patients. Am J Psychiatry 155:536-542.

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